Institute & Campus July 24, 2018 By Jana Schlütter Custom-made proteins If a project is missing a certain protein, such as an antibody, Anja Schütz can help. The biochemist has been leading the Protein Production and Characterization Platform at the MDC since May 2018.
Science November 07, 2017 Message transmitters at work When your heart beats faster during states of excitement, G protein-coupled receptors (GPCRs) have...
Science October 09, 2017 A protein in the brain links body weight, metabolism and activity For many obese people gaining weight is a vicious cycle. Scientists at the MDC have now uncovered a contributing factor: genetic variants linked to obesity cause the brain to produce too much of a protein called Cadm1. The result is a disruption in the regulation of body weight and changes in behavior and metabolism, as reported by Matthew Poy and his colleagues in Nature Neuroscience.
Press Release No. 12 June 01, 2017 Berlin The art of folding mitochondrial membranes Oliver Daumke’s lab figures out how the inner membranes of mitochondria “get their groove” and assume the complex shapes they need to carry out crucial cellular functions
Science March 23, 2017 New study shows circular RNA can encode for proteins A group of scientists in Israel and Germany, led by Prof. Sebastian Kadener from the Hebrew University of Jerusalem, have discovered a protein-encoding function for circular RNA. This kind of RNA molecule is highly active in brain cells and could play an important role in neurodegenerative diseases.
Science February 23, 2017 How proteins reshape cell membranes Small “bubbles” frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins – a focus of research by Oliver Daumke of the MDC. He and his team have now shed light on how these proteins assemble on the surface of a cell and reshape its membrane.
Science December 15, 2016 Only apparently healthy: How titin gene mutations affect heart function The MDC research group led by Norbert Hübner has discovered that mutations in the titin gene have previously unknown effects on the heart function of healthy individuals. These mutations are present in one percent of the general population.
Science November 21, 2016 New multinational study reveals titin gene mutations affect heart function in healthy individuals A new multinational study by researchers from Singapore, the UK and Germany has discovered that gene mutations in a protein called titin affect the heart function in healthy individuals. It was previously thought that the mutations affect only patients with dilated cardiomyopathy, one of the most common forms of inherited heart disease.
Science October 28, 2016 #LabHacks: Blocking sticky proteins with milk powder Eating and drinking is strictly forbidden in the lab, as everyone knows. So why is milk powder often found on the shelves? Here is the explanation…
Press Release No. 43 October 11, 2016 Berlin The life cycle of proteins What’s the life of a protein like? First, a blueprint is transcribed from a gene and eventually...